Providing Expert Diagnosis

Our physicians and staff have the expertise to help you manage your Multiple Sclerosis

Infusion Center

Outpatient intravenous antibiotic therapy

Research / Clinical Trials

Our practice offers clinical trials which help determine whether newly developed treatments are safe and effective in treating Multiple Sclerosis.

SPECIAL HOURS:  Our office will be closed July 4th and 5th. We will reopen Monday at our normal hours.

2024 will see more great changes at Hope as we take back our infusion center.

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Our goal is to improve the health, hope, and well-being of MS patients by providing state of the art treatment, advocacy, patient education, and clinical research leading to a more promising outlook for our clients.


2060 Lakeside Center Way
Knoxville, TN 37922
865.218.6222 Phone
833-671-1059 Fax

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Monday-Thursday 8am – 4:30pm

Payment Portal

Patients can now make their payments for the current system on the patient portal. For all old balances prior to 9/12/22 patients will need to pay through the current link on the website or call the office so that their payment may be applied appropriately.

New Patient Portal


We are excited to announce that Jo Ella Clark, Licensed Professional Counselor, LPC MHSP will be hosting our next support group on March 21st at 6:00 PM.

Jo Ella has worked for the past 19 years with adults, adolescents, and children, addressing a variety of issues including behavioral concerns, a variety of mental health diagnoses, trauma, addiction, self-harm, depression, anxiety, family issues, and more. I have also worked with adults in a variety of settings to address marriage and family concerns as well as addiction, trauma, and parenting skills.
Jo Ella will be talking about Seasonal Depression and MS. While there is a stigma that seasonal depression revolves around the winter months, for many MS patients it can also hit hard for summer as the heat intolerance comes to a head. She will be sharing ways for patients and family members to transition and cope through the seasons.


  • 1/2/2024      Observance of New Year
  • 1/15/2024     Martin Luther King Day
  • 5/27/2023     Memorial Day
  • 7/4/2024        July 4 Holiday
  • 9/2/2024        Labor Day
  • 11/27/2024    Closed at 2:00
  • 11/28/2024    Thanksgiving All Day
  • 12/25/2024    Christmas Day


Dr. David Brandes Announcement

Dear Patients: The purpose of this letter is to let you know of my plans for retirement. On June 02, 2022 I will be retiring from the practice of medicine.I enjoyed my years of service to my patients and my community practicing Neurology in Knoxville and California....

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What You Need to Know about the Covid Booster

What You Need to Know about the Covid Booster

People who are moderate to severely immunocompromised are especially vulnerable to COVID-19 because they are more at risk of serious, prolonged illness. People with moderately to severely compromised immune systems may not build the same level of immunity to the...

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